Haodi Zou

The Center for Disease Control estimates that 6 in 10 adults in the United States live with a chronic disease such as cancer, heart disease, or diabetes. Yet most patients lack sufficient access to comprehensible information and guidance for effective self-management of chronic conditions and remain unaware of gaps in their knowledge. To address this challenge, we introduce SAGE, a System for Accessible Guided Exploration of healthcare information. SAGE is an information system that leverages Large Language Models (LLMs) to help patients identify and fill gaps in their understanding through automated organization of healthcare information, generation of guiding questions, and retrieval of reliable and accurate answers to patient queries. While LLMs may be a powerful intervention for these tasks, they pose risks and lack reliability in such high-stakes settings. One approach to address these limitations is to augment LLMs with Knowledge Graphs (KGs) containing well-structured and pre-verified health information. Thus, SAGE demonstrates how LLMs and KGs can complement each other to aid in the construction and retrieval of structured knowledge. By integrating the flexibility and natural language capabilities of LLMs with the reliability of KGs, SAGE seeks to create a collaborative system that promotes knowledge discovery for informed decision-making and effective self-management of chronic conditions.